Disease - EDK - BIG Data Center

Disease name	Basal Cell Carcinoma
Classfication	Cancer
Related Enzyme(s)
EFO	EFO:0004193
DOID	2513
OMIM	OMIM:605462 OMIM:613058 OMIM:613059 OMIM:613061 OMIM:613062 OMIM:613063
NCI	NCI:C2921
Definition	Basal-cell carcinoma, is the most common type of skin cancer. It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it; or it may present as a raised area with ulceration.

mRNA

Gene symbol	Species	Enzyme	Editing site(s)	Editing Type	PMID	RADAR	REDIportal	Description
IGFBP7	Human	ADAR1;ADAR2	3	A-to-I	28035363 23543219			RNA editing in IGFBP7 promotes cell apoptosis in the tumor, but the inadequate A-to-I editing of IGFBP7 may be used by tumor cells to escape the cellular control of proliferation.